Product Overview
SS-31 (Elamipretide) is a synthetic research compound supplied by Arche Research as a lyophilized material for lawful laboratory, analytical, and non-clinical research. Multiple nominal quantities are available through the strength selector on this page.
Research Context
SS-31 has been examined in published preclinical and clinical research involving its activity as a mitochondria-targeted peptide that selectively localizes to the inner mitochondrial membrane. Investigations have primarily focused on its high-affinity binding to cardiolipin, its role in stabilizing mitochondrial cristae structure, and its capacity to reduce reactive oxygen species (ROS) and reverse mitochondrial dysfunction in cardiac, renal, and skeletal muscle clinical and preclinical trial settings. The references provided below are included to identify relevant scientific literature and do not constitute product-use, medical, or administration guidance.
Research References
- Szeto HH, et al. “Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury.” Journal of the American Society of Nephrology. 2011;22(6):1041-1052. DOI: 10.1681/ASN.2010080808.
- Sabbah HN, et al. “Chronic Therapy With Elamipretide (MTP-131), a Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure.” Circulation: Heart Failure. 2016;9(5):e002206. DOI: 10.1161/CIRCHEARTFAILURE.115.002206.
