Product Overview
Nicotinamide adenine dinucleotide is an essential coenzyme used throughout cellular metabolism. It carries electrons during redox reactions, supports mitochondrial ATP production, and serves as a required substrate for enzymes involved in stress response, DNA repair, and gene regulation.
Research interest in NAD+ is driven by its central role in mitochondrial function and by the observation that NAD+ availability changes with age and metabolic stress. Common study areas include sirtuin signaling, PARP-mediated DNA repair, oxidative stress, cellular resilience, neuroenergetics, and the metabolic consequences of declining NAD+ pools.
For energy-metabolism and longevity research, NAD+ is not a side pathway – it is part of the cellular operating system.
Common Research Areas
⦁ Mitochondrial respiration and ATP production
⦁ Redox and electron-transfer reactions
⦁ Sirtuin signaling
⦁ PARP and DNA-repair pathways
⦁ Cellular aging and metabolic resilience
Research References
- Verdin E. “NAD+ in biology and disease.” Nature Reviews Molecular Cell Biology. 2015;16(9):533-541. DOI: 10.1038/nrm4030.
- Fang EF, et al. “NAD+ in aging: molecular mechanisms and translational implications.” Trends in Molecular Medicine. 2017;23(10):899-916. DOI: 10.1016/j.molmed.2017.08.005.
